The key to metabolic mastery is in ones’ ability to regulate the cell, more specifically the mitochondria. Most, if not all illness involves a lack of energy, therefore supporting mitochondria is key. Think of mitochondria like a battery.
There are multiple reasons this happens, trauma (emotional and physical), toxicity, infection, and nutritional deficiencies. Collectively these inhibit and compromise the production of ATP, the energy currency of each cell.
I will list some nutritional supplements to support this, and will touch on the other reasons briefly.
What Causes Mitochondrial Dysfunction?
Stress, Trauma and the Nervous System
Trauma chronically activates the HPA axis, creating sympathetic dominance. Over time this reprograms the mitochondria by over signalling. This stress can lead to a cell danger response, in which the mitochondria produce less energy and shift into survival mode. Modalities to support this are, but not limited to; somatic work, breathing exercises, meditation, humming, cold exposure, vagal stimulation and neural therapy. (refer to nutritional support below).
Toxins, Infections and the Cellular Environment
Toxicity arises from multiple sources, such as glyphosates, fertilisers, EMFs, heavy metals, mold and “forever chemicals”. (refer to nutritional support below).
Infection is a double edged sword, on the one hand based on the germ theory, on the other the terrain theory. Basically is it the bug or the terrain? Either way we focus on supporting the body allowing for the immune system to ‘do its job,’ whilst utilising microbial, parasitic and viral supplements to support this.
Nutritional Support for the Vagus Nerve and Cell Membranes
Nutritional supplements I recommend for vagus nerve support
B‑complex and thiamine (B1)
For vagus nerve signaling and energy, I use Objective Nutrients B Complex plus their high‑dose B1 (Benfotiamine and/or TTFD), and I also like Life Extension Benfotiamine and Vitality Pro Benfotiamine.
Choline and acetylcholine support
Because acetylcholine is the main neurotransmitter of the vagus nerve, I often recommend BodyBio Phospholipid Complex, Vitality Pro Alpha GPC and Jarrow Formulas CDP‑Choline.
Magnesium for nerve relaxation
Magnesium is essential for nerve transmission and parasympathetic “calm”; magnesium glycinate is my go‑to form, and we stock several high‑quality brands in this form.
Essential fatty acids and membranes
For neuronal membrane structure and vagal anti‑inflammatory signalling, I like omega‑3‑rich fish or krill oil, or “parent essential oil” blends from brands such as BodyBio and Yes.
Nutritional Factors in Mitochondrial Biochemistry
Nutritional mitochondrial support
CoQ10 (ubiquinol)
I recommend ubiquinol CoQ10 from Life Extension, Pharma Nord, and Researched Nutritionals. It serves as a key electron carrier in the mitochondrial electron transport chain and acts as a strong antioxidant, helping protect mitochondrial membranes and DNA from oxidative damage.
Niacin and NAD⁺ precursors (NR, NMN)
Niacin (vitamin B3), as well as NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide), all contribute to building and maintaining NAD⁺ pools, which are essential for mitochondrial energy production, redox reactions, DNA repair, and sirtuin activity. For NAD⁺ support, I recommend Quicksilver products; for NR, Niacel by Thorne; for NMN, Purevitalis; and for niacin, Seeking Health.
PQQ
I recommend PQQ from Designs for Health and Seeking Health. PQQ supports mitochondrial biogenesis (the formation of new mitochondria) and has redox-modulating and antioxidant effects, which can enhance mitochondrial efficiency and resilience.
Mitochondrial ATP nutrient combinations
I recommend comprehensive mitochondrial formulations such as BC-ATP by Cellcore Biosciences and ATP 360 by Researched Nutritionals. These combination products typically include multiple mitochondrial cofactors (e.g., B vitamins, CoQ10, carnitine, antioxidants, phospholipids) to support ATP production at several steps, stabilize mitochondrial membranes, and reduce oxidative stress in a more integrated way than single agents.
Magnesium is the main mineral directly required for ATP because ATP works in the body as Mg‑ATP. Other
important minerals that support ATP production and energy metabolism include iron, copper, zinc,
manganese, chromium, selenium, and iodine.
I have outlined the main nutrients that play a key role in supporting mitochondrial ATP production; this list is not exhaustive, but it covers many of the most commonly used and well‑studied options.
Alongside targeted supplementation, photobiomodulation (red and near‑infrared light therapy) can help upregulate mitochondrial ATP production in exposed tissues.
Binders and Toxin‑Focused Strategies
Toxin removal
Ultra Binder (Quicksilver)
Broad‑spectrum gut binder using charcoal, clays, zeolite, chitosan, and modified citrus pectin to mop up metals, mycotoxins, LPS, and chemicals in the GI tract. Best as a “universal” mop during detox phases.
BioToxin Binder (CellCore)
Systemic fulvic‑based “carbon” binder targeting biotoxins (mycotoxins, microbial waste, ammonia) and supporting cellular energy. Often used early to stabilise terrain and drainage before heavier metal work.
HM‑ET Binder (CellCore)
Similar carbon technology, tuned more toward heavy metals and environmental toxins. Typically layered in after BioToxin Binder once drainage and general toxin burden are better controlled.
Toxaprevent (MANC clinoptilolite)
Non‑absorbed zeolite clinoptilolite that stays in the gut and binds positively charged compounds like histamine, ammonium, and certain metals/mycotoxins. Excellent for gut‑dominant issues and histamine or ammonia overload
Chlorella
Nutrient‑dense algae with a binding cell wall that gently helps sequester heavy metals and some pollutants in the gut, suitable for longer‑term, food‑like support and as an adjunct to more targeted binders.
TOX‑EASE BIND™
A detox formula combining flaxseed fibre, shilajit (fulvic acid), activated charcoal, and beta‑sitosterol to bind and eliminate a broad range of toxins while supporting gut and cellular health. It aims to move metals, mycotoxins, and fat‑soluble neurotoxins out of the body without heavily depleting nutrients.
Drainage, Liver–Bile Flow and Excretion Pathways
Drainage
Bowel support
Qenda acts as a bowel mover, kills parasites and helps bind toxins. Bowel Mover by Cellcore moves the bowel. Para 1, 2 & 3 helps reduce the parasite load.
Kidney and lymphatic support
At the same time, you “open drainage” supporting liver and bile flow (Drainage Activator, liver-focused products), and helping kidneys and lymph (KL Support and LymphActiv) so the kidneys and lymphatic system can clear what’s mobilised.
Liver and bile support
Liver Sauce (Quicksilver) is used to stimulate liver and bile detox, so pairing it with binders means what the liver dumps into bile is more likely to be bound in the gut and excreted rather than reabsorbed.
Overall idea: don’t just kill parasites or stir up toxins; make sure bowels, liver–bile, kidneys and lymph are all supported so die‑off and detox are smoother and you feel fewer symptoms.