RRP £70.95

It has been well established in the scientific medical literature that mitochondrial dysfunction, with its associated ATP deficiency, is related to a host of diseases, including degenerative neurological disorders (i.e., Alzheimer’s, Parkinson’s, multiple sclerosis, amyotrophic lateral sclerosis), cardiovascular disease (i.e., heart attack, stroke, peripheral vascular disease), obesity, and diabetes (reduced mitochondrial biogenesis has been demonstrated in metabolic syndrome).

Mitochondria deteriorate with age due to ongoing exposure to free radicals, which accelerate the destruction of cellular components. As the mitochondrial function declines the cells become starved for energy and damaged, causing them to function less efficiently. Many investigators suspect that caloric restriction slows aging primarily by lowering free radical production in mitochondria. Conversely, the benefits of increased mitochondrial biogenesis and ATP availability are many, including the reduction of oxidative stress and age–related deterioration as well as improvements in metabolic function, energy level, exercise performance, body composition, cognitive function, and lifespan (shown in animal models).